Nicotine (Nicoderm) transdermal drug delivery system can be applied to the following skin site:

• A. Arm
• B. Upper chest
• C. Behind ear
• D. Back

Answer: (C)

Transdermal patches rely on clean, intact skin that allows steady drug absorption over time. The area behind the ear provides relatively thin, smooth, and hairless skin with good blood flow, so the nicotine can diffuse consistently and the patch adheres well. It’s also discreet and less likely to be rubbed off by clothing or affected by arm movement, which helps maintain a steady delivery over the 24-hour wear period. While other sites like the arm, upper chest, or back can be used, behind the ear is particularly practical for keeping the patch in place and ensuring reliable absorption. Always apply to clean, dry skin and rotate sites to reduce irritation.